A viable approach to convert seafood by-products into commercially profitable products is “seafood flavor manufacturing”, since flavor is considered a high value product and good quality seafood flavors are in high demand. The production of natural seafood flavor extracts from the process by-products has been an industrial practice in France and Japan. As a common industrial practice, natural seafood flavors are reformulated by adding other ingredients and artificial flavors for desired flavor characteristics. Seafood flavors are being used in seafood sauces, chowders, soups, bisques, instant noodles, snacks, and surimi seafood. In seafood entreÂe, the use of good flavored sauce is critical to the acceptability of the meal. An analogy is that one may not eat salad without the dressing of one's choice. There are three basic process routes for making seafood flavors from finfish and shellfish processing by-products, namely, aqueous extraction, fermentation, and enzymatic hydrolysis.