Fibroblasts in Kidney Fibrosis Emerge via Endothelial-to-Mesenchymal Transition

间充质干细胞 纤维化 上皮-间质转换 医学 成纤维细胞 过渡(遗传学) 肾脏疾病 病理 细胞生物学 癌症研究 生物 内分泌学 细胞培养 遗传学 基因
作者
Elisabeth M. Zeisberg,Scott Potenta,Hikaru Sugimoto,Michael Zeisberg,Raghu Kalluri
出处
期刊:Journal of The American Society of Nephrology 卷期号:19 (12): 2282-2287 被引量:824
标识
DOI:10.1681/asn.2008050513
摘要

In June 2017, a media frenzy ensued after Michelle Carter was convicted of involuntary manslaughter in the state of Massachusetts for facilitating the suicide of Conrad Roy. The verdict stirred controversy and cast a spotlight on facilitation of suicide, i.e., a person9s act(s) done with the purpose of helping another to die by suicide. One form of facilitation, physician-assisted suicide, has been extensively debated in the existing literature. In this article, we set out to explore the legal and forensic ramifications of non–physician-assisted suicide, which we refer to as facilitated suicide. We first conducted a review of all fifty states9 legislation regarding facilitated suicide: forty-four states prohibit it by statute, and three states prohibit it through common law. Thirteen states specifically outlaw verbal facilitation of suicide. We then surveyed the case law to identify legal precedent to the Commonwealth v. Carter verdict. Final Exit Network, Inc. v. State and State v. Melchert-Dinkel provide contrasting yet complementary perspectives on the interplay between speech and assisted suicide. Finally, we detailed the role of forensic psychiatry in investigating facilitated suicide, specifically among adolescents and youths.

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