Response to a letter by Dr T Ramesh

The Author reply, We thank Dr Ramesh and colleagues in their letter1 for drawing our attention to their recent, important paper,2 showing very early, preclinical abnormalities in a Zebrafish model of amyotrophic lateral sclerosis (ALS), which we overlooked in our recent review, ‘Amyotrophic lateral sclerosis: a long preclinical period?’3 The Zebrafish findings are completely supportive …