摘要
European Journal of BiochemistryVolume 179, Issue 2 p. 255-266 Free Access Molecular mechanism of visual transduction Marc CHABRE, Corresponding Author Marc CHABRE Laboratoire de Biophysique Moléculaire et Cellulaire (Unité Associée 520 au CNRS), Département Recherche Fondamentale, Centre ďÉtudes Nucléaires, GrenobleCorrespondence to M. Chabre, Laboratoire de Biophysique Moléculaire et Cellulaire. CENG Boîte Postale 85X, F-38041 Grenoble, FranceSearch for more papers by this authorPhilippe DETERRE, Philippe DETERRE Laboratoire de Biophysique Moléculaire et Cellulaire (Unité Associée 520 au CNRS), Département Recherche Fondamentale, Centre ďÉtudes Nucléaires, GrenobleSearch for more papers by this author Marc CHABRE, Corresponding Author Marc CHABRE Laboratoire de Biophysique Moléculaire et Cellulaire (Unité Associée 520 au CNRS), Département Recherche Fondamentale, Centre ďÉtudes Nucléaires, GrenobleCorrespondence to M. Chabre, Laboratoire de Biophysique Moléculaire et Cellulaire. CENG Boîte Postale 85X, F-38041 Grenoble, FranceSearch for more papers by this authorPhilippe DETERRE, Philippe DETERRE Laboratoire de Biophysique Moléculaire et Cellulaire (Unité Associée 520 au CNRS), Département Recherche Fondamentale, Centre ďÉtudes Nucléaires, GrenobleSearch for more papers by this author First published: February 1989 https://doi.org/10.1111/j.1432-1033.1989.tb14549.xCitations: 273 This review is dedicated to the memory of our friend hermann kühn, a poineer of the biochemistry of visual transduction AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abbreviations ROS rod outer segment R* photoexcited rhodopsin T2GDP T2GTP, T2empty, α-subunit of transducin bearing a GDP, a GTP, or with an empty site T Tγ, β and γ subunit of transducin PDE cGMP-specific phosphodiesterase PDEαβ catalytic subunits of PDE I inhibitory subunit of PDE GDP[βS] guanosine 5′-[β-thio]diphosphate GTP[γS] guanosine 5′-[γ-thio]triphosphate GuoPP[NH]P guanosine 5′-[β,γ-imino]triphosphate Enzymes cGMP-specific phosphodiesterase (EC 3.1.4.35) guanylate cyclase (EC 4.6.1.2) REFERENCES 1a. Stryer, L. (1986) Annu. Rev. Neurosci. 9, 87– 119. CrossrefCASPubMedWeb of Science®Google Scholar 1b. Nathans, J. (1987) Annu. Rev. Neurosci. 10, 163– 194. CrossrefCASPubMedWeb of Science®Google Scholar 2 Applebury, M. L. & Hargrave, P. A. (1986) Vision Res. 26, 1881– 1895. CrossrefCASPubMedWeb of Science®Google Scholar 3a. Pugh, E. N. (1987) Annu. Rev. Physiol. 49, 715– 742. 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