A clinical study of preoperative endoscopic assessment of the invasion depth of colorectal laterally spreading tumor

Objective To compare the diagnostic accuracy of magnifying chromoendoscopy (MCE) and endoscopic ultrasonography (EUS) for preoperative endoscopic assessment of the invasion depth of colorectal laterally spreading tumour(LST). Methods Data of 104 cases of colorectal LST were included. With the final pathological diagnosis as the golden standard, the accuracies of MCE and EUS for preoperative assessment of the invasion depth of colorectal LST were compared. Results The diagnostic accuracies of MCE and EUS for evaluating the invasion depth of LST were 89.4%(93/104) and 73.1%(76/104), respectively(P<0.05). The lesion size and the endoscopist could affect the accuracy of the EUS evaluation(P=0.017, OR=3.561; P=0.035, OR=1.399). The accuracy of EUS seemed to show a downward trend for colorectal LST of larger diameters. Conclusion Both MCE and EUS are effective for evaluating the invasion depth of colorectal LST, but the accuracy of MCE may be higher than that of EUS. Large diameter of the lesion and the doctor's experience inadequacy may be the risk factors for the accuracy of EUS. Key words: Colorectal neoplasms; Endosonography; Program evaluation; Laterally spreading tumor; Magnifying chromoendoscopy