脂多糖
化学
基因
脂质代谢
发病机制
脂多糖结合蛋白
同源(生物学)
生物化学
医学
免疫学
受体
CD14型
标识
DOI:10.1007/978-981-15-6082-8_3
摘要
Lipopolysaccharide-binding protein (LBP) and bactericidal/permeability-increasing protein (BPI) are the main members of BPI-like family based on the similar protein structure and conserved gene homology. Both LBP and BPI participate in lipid metabolism and thereby involve in pathogenesis of certain cardiovascular diseases. This chapter describes four aspects: (1) the loci of BPI and LBP in genome, (2) the characteristics of the cDNAs and expression patterns of LBP and BPI, (3) the structures and functions of LBP and BPI, and (4) the LBP and BPI in lipid metabolism and cardiovascular research.
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