Intranasal delivery of self-assembled nanoparticles of therapeutic peptides and antagomirs elicits anti-tumor effects in an intracranial glioblastoma model
胶质母细胞瘤
鼻腔给药
医学
药理学
癌症研究
作者
Junkyu Ha,Minkyung Kim,Youngki Lee,Minhyung Lee
出处
期刊:Nanoscale [The Royal Society of Chemistry] 日期:2021-01-01卷期号:13 (35): 14745-14759被引量:19
标识
DOI:10.1039/d1nr03455c
摘要
Self-assembled nanoparticles were produced solely with therapeutic agents, antagomir-21 and RAP. The therapeutic effects of the nanoparticles by intranasal delivery were evaluated in intracranial glioblastoma animal models.