再狭窄
祖细胞
内皮干细胞
生物
内皮祖细胞
血管
血管生成
细胞生物学
内膜增生
新生内膜增生
内皮
干细胞
内科学
体外
内分泌学
医学
生物化学
支架
平滑肌
作者
Linzhen Xia,Jun Tao,Yanjun Chen,Lingli Liang,Guifang Luo,Zemin Cai,Wang Zuo
标识
DOI:10.1089/dna.2021.0082
摘要
The vascular endothelium, which plays an essential role in maintaining the normal shape and function of blood vessels, is a natural barrier between the circulating blood and the vascular wall tissue. The endothelial damage can cause vascular lesions, such as atherosclerosis and restenosis. After the vascular intima injury, the body starts the endothelial repair (re-endothelialization) to inhibit the neointimal hyperplasia. Endothelial progenitor cell is the precursor of endothelial cells and plays an important role in the vascular re-endothelialization. However, re-endothelialization is inevitably affected in vivo and in vitro by factors, which can be divided into two types, namely, promotion and inhibition, and act on different links of the vascular re-endothelialization. This article reviews these factors and related mechanisms.
科研通智能强力驱动
Strongly Powered by AbleSci AI