大疱性类天疱疮
获得性大疱性表皮松解症
类天疱疮
医学
皮肤病科
介绍(产科)
天疱疮
免疫学
外科
抗体
作者
Valeryia Pratasava,Vikram N Sahni,Aishwarya Suresh,Simo Huang,Abhirup Are,Sylvia Hsu,Kiran Motaparthi
标识
DOI:10.3390/medicina57101061
摘要
The pemphigoid family of dermatoses is characterized by autoimmune subepidermal blistering. The classic paradigm for pemphigoid, and the most common member, is bullous pemphigoid. Its variable clinical presentation, with or without frank bullae, is linked by significant pruritus afflicting the elderly. Mucous membrane pemphigoid is an umbrella term for a group of subepidermal blistering dermatoses that favor the mucosal membranes and can scar. Epidermolysis bullosa acquisita is a chronic blistering disorder characterized by skin fragility, sensitivity to trauma, and its treatment-refractory nature. Clinicians that encounter these pemphigoid disorders may benefit from an overview of their clinical presentation, diagnostic work-up, and therapeutic management, with an emphasis on the most frequently encountered pemphigoid disease, bullous pemphigoid.
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