A novel analytical strategy for the determination of perfluoroalkyl acids in various food matrices using a home-made functionalized fluorine interaction SPME in combination with LC-MS/MS

In this study, a fluorine-fluorine interaction approach through fluoridating boron nitride nanosheets (BNNs) for sensing perfluoroalkyl acids (PFAAs) in multiple food matrices was developed. Through a facile hydrothermal fluorination modification, the BNNs were transferred into homogeneous fluorinated boron nitride nanoparticles (F-BNNs) with robust networks and specific surface area. After morphological modification, the particles displayed strong adsorption and sensing capabilities on PFAAs in both solid and liquid food matrix. Under the evaluation of mass spectrometry, F-BNNs based microextraction approach exhibited low method detection limits (MDLs) in the ranges of 0.9–3.9 pg mL−1 and 3.6–15.8 pg g−1 for milk and meat matrices, respectively, with satisfactory repeatability (RSD% <13.5%) and recoveries (77.7–110.5%). This work not only depicted a facile approach for preparing F-BNNs based SPME fiber, but also provided a routine analysis protocol for monitoring PFAAs in food systems.