神经调节
迷走神经电刺激
磁刺激
神经炎症
脑深部刺激
经颅直流电刺激
医学
脑刺激
神经科学
心情
情绪障碍
电休克疗法
焦虑
萧条(经济学)
心理学
刺激
精神科
炎症
精神分裂症(面向对象编程)
迷走神经
内科学
帕金森病
疾病
经济
宏观经济学
作者
Bingqi Guo,Meng-Yao Zhang,Wensi Hao,Yuping Wang,Tingting Zhang,Chunyan Liu
标识
DOI:10.1038/s41398-022-02297-y
摘要
Abstract Mood disorders are associated with elevated inflammation, and the reduction of symptoms after multiple treatments is often accompanied by pro-inflammation restoration. A variety of neuromodulation techniques that regulate regional brain activities have been used to treat refractory mood disorders. However, their efficacy varies from person to person and lack reliable indicator. This review summarizes clinical and animal studies on inflammation in neural circuits related to anxiety and depression and the evidence that neuromodulation therapies regulate neuroinflammation in the treatment of neurological diseases. Neuromodulation therapies, including transcranial magnetic stimulation (TMS), transcranial electrical stimulation (TES), electroconvulsive therapy (ECT), photobiomodulation (PBM), transcranial ultrasound stimulation (TUS), deep brain stimulation (DBS), and vagus nerve stimulation (VNS), all have been reported to attenuate neuroinflammation and reduce the release of pro-inflammatory factors, which may be one of the reasons for mood improvement. This review provides a better understanding of the effective mechanism of neuromodulation therapies and indicates that inflammatory biomarkers may serve as a reference for the assessment of pathological conditions and treatment options in anxiety and depression.
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