肾功能
医学
受体
肾
功能(生物学)
内分泌学
泌尿科
内科学
细胞生物学
生物
作者
Yang Xu,Anne‐Laure Faucon,Edouard L. Fu,Juan Jesús Carrero
标识
DOI:10.1016/j.kint.2023.06.009
摘要
In the analysis of SUSTAIN-6 (the Trial to Evaluate Cardiovascular and Other Long-term Outcomes With Semaglutide in Subjects With Type 2 Diabetes)/PIONEER-6 (the Trial Investigating the Cardiovascular Safety of Oral Semaglutide in Subjects With Type 2 Diabetes) trials by Tuttle et al.,1 semaglutide, a glucagon-like peptide-1 receptor agonist (GLP1-RA), was associated with a slower estimated glomerular filtration rate (eGFR) decline versus placebo, with a mean difference in eGFR slope of 0.59 ml/min per 1.73 m2 per year.
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