Mechanical Circulatory Support Infections

Chapter 65 Mechanical Circulatory Support Infections Gerard Giblin MD, Gerard Giblin MDSearch for more papers by this authorCiara O'Connor MD, Ciara O'Connor MDSearch for more papers by this authorEmer Joyce MD, PhD, Emer Joyce MD, PhDSearch for more papers by this authorMargaret M. Hannan MD, Margaret M. Hannan MDSearch for more papers by this author Gerard Giblin MD, Gerard Giblin MDSearch for more papers by this authorCiara O'Connor MD, Ciara O'Connor MDSearch for more papers by this authorEmer Joyce MD, PhD, Emer Joyce MD, PhDSearch for more papers by this authorMargaret M. Hannan MD, Margaret M. Hannan MDSearch for more papers by this author Book Editor(s):Yaron D. Barac, Yaron D. BaracSearch for more papers by this authorScott C. Silvestry, Scott C. SilvestrySearch for more papers by this authorMani A. Daneshmand, Mani A. DaneshmandSearch for more papers by this authorDaniel J. Goldstein, Daniel J. GoldsteinSearch for more papers by this author First published: 08 September 2023 https://doi.org/10.1002/9781119633884.ch65 AboutPDFPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShareShare a linkShare onEmailFacebookTwitterLinkedInRedditWechat Abstract Mechanical circulatory support (MCS), encompassing ventricular assist devices (VADs) and total artificial hearts (TAHs), is now a well-established treatment for patients with advanced heart failure. The term MCS and VAD refers to durable left VADs (LVADs) and right VADs, biventricular assist devices, and TAHs. While most of the available literature applies to LVADs and outcomes vary across the range of MCS devices, the same general principles relating to infection apply to each device. This chapter provides a comprehensive overview of the spectrum of infection occurring in patients with durable MCS devices by outlining the epidemiology, definitions, microbiology, diagnosis, prevention, management, and prognosis of these infections. Ultrasonography can be used to visualize fluid collections around the course of a VAD driveline as well as the pump pocket provided the patient has favorable sonographic windows for imaging deeper structures, but in general it is of little value in the assessment of pump-related infection. References Goldstein DJ , Meyns B , Xie R , et al. Third annual report from the ISHLT mechanically assisted circulatory support registry: a comparison of centrifugal and axial continuous-flow left ventricular assist devices . J Heart Lung Transplant . 2019 ; 38 ( 4 ): 352 – 363 . 10.1016/j.healun.2019.02.004 PubMedWeb of Science®Google Scholar de By T , Mohacsi P , Gahl B , et al. 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