CeF3-YF3-TbF3 Nanoparticle-Polymer–“Radachlorin” Conjugates for Combined Photodynamic Therapy: Synthesis, Characterization, and Biological Activity

Promising material for hybrid photodynamic therapy consisting of Ce0.5Y0.35Tb0.15F3 crystalline nanoparticles and Radachlorin is reported. One possible option of conjugation of Ce0.5Y0.35Tb0.15F3 nanoparticles and Radachlorin using polyethylenimine (PEI) is tested. The energy transfer reaches 28%. It is shown that conjugates of CeF3—Tb3+ NPs and Radachlorin using PEI—are stable, and the distance between nanoparticles and photosensitizer molecules is about 5 nm.