业务
药学
生化工程
材料科学
纳米技术
药理学
医学
工程类
作者
Rachana D Pockle,Rajashree Masareddy,Archana S. Patil,Pragati D Patil
出处
期刊:Therapeutic Delivery
[Newlands Press Ltd]
日期:2023-07-01
卷期号:14 (7): 443-458
被引量:9
标识
DOI:10.4155/tde-2023-0026
摘要
The effectiveness of pharmaceutical drugs depends not only on their active components and manufacturing processes, but also on the role played by pharmaceutical excipients. The traditional definition of excipients as inactive and cost-effective substances has evolved significantly. They are now recognized as essential elements of drug formulations, constituting 80-90% of the final product. The rapid advancements in delivery systems, along with scientific, regulatory, financial and technological developments in biopharmaceutics, have generated renewed interest in the use and functionality of excipients, especially in solid dosage forms. This review focuses on the categorization of excipients according to the International Pharmaceutical Excipient Council (IPEC) and the establishment of guidelines for evaluating the safety of a new proposed excipient.Excipients are matter we add to medicine when we make it. They give the medicine different qualities, like making it easier to dissolve, stick together, or slide smoothly. But if we use too many excipients, it can make the medicine less stable and more expensive. To avoid these problems, we can use special excipients that can do more than one thing. These multi-purpose excipients make the medicine work better, stay stable and cost less.
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