Lipid Nanoparticles for Oral Delivery of Nucleic Acids for Treating Inflammatory Bowel Disease

NanomedicineVol. 17, No. 21 EditorialLipid nanoparticles for oral delivery of nucleic acids for treating inflammatory bowel diseaseChunhua Yang, Gianfranco Alpini, Shannon Glaser & Didier MerlinChunhua Yang *Author for correspondence: E-mail Address: cyang16@gsu.eduhttps://orcid.org/0000-0003-0805-1008Institute for Biomedical Sciences, Digestive Disease Research Group, Georgia State University, Atlanta, GA 30303, USAResearch, Atlanta Veterans Affairs Medical Center, Decatur, GA 30302, USA, Gianfranco AlpiniDepartment of Medicine, Division of Gastroenterology & Hepatology, Indiana University School of Medicine, Indianapolis, IN 46220, USAResearch, Richard L. Roudebush VA Medical Center, Indianapolis, IN 46202, USA, Shannon GlaserDepartment of Medical Physiology, Texas A&M University School of Medicine, Bryan, TX 77807, USA & Didier MerlinInstitute for Biomedical Sciences, Digestive Disease Research Group, Georgia State University, Atlanta, GA 30303, USAResearch, Atlanta Veterans Affairs Medical Center, Decatur, GA 30302, USAPublished Online:1 Nov 2022https://doi.org/10.2217/nnm-2022-0222AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInReddit View articleKeywords: Crohn's diseasegene therapyplant-derived lipid nanoparticlessolid lipid nanoparticlestargeted drug deliveryulcerative colitisPapers of special note have been highlighted as: • of interest; •• of considerable interestReferences1. Zhang W, Michalowski CB, Beloqui A. Oral delivery of biologics in inflammatory bowel disease treatment. Front. Bioeng. 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Commun. 9(1), 4493 (2018).Crossref, Medline, Google ScholarFiguresReferencesRelatedDetails Vol. 17, No. 21 Follow us on social media for the latest updates Metrics Downloaded 57 times History Received 29 August 2022 Accepted 11 October 2022 Published online 1 November 2022 Published in print September 2022 Information© 2022 Future Medicine LtdKeywordsCrohn's diseasegene therapyplant-derived lipid nanoparticlessolid lipid nanoparticlestargeted drug deliveryulcerative colitisAuthor contributionsConceptualization: C Yang and D Merlin; writing – original draft preparation: C Yang; writing – review and editing: G Alpini, S Glaser and D Merlin; all authors have read and agreed to the version of the manuscript.Financial & competing interests disclosureThis research was funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), grant nos. RO1DK107739 (D Merlin), RO1DK116306 (D Merlin) and R01DK132891 (G Alpini and S Glaser), and Department of Veterans Affairs (BX002526, D Merlin). A portion of this work was supported by the Hickam Endowed Chair, Gastroenterology, Medicine, Indiana University grant, and the Indiana University Health–Indiana University School of Medicine Strategic Research Initiative grant to G Alpini. D Merlin and G Alpini are recipients of a Senior Research Career Scientist Award (BX004476) from the Department of Veterans Affairs. The views expressed in this article are those of the authors and do not necessarily represent the views of the Department of Veterans Affairs. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.No writing assistance was utilized in the production of this manuscript.PDF download