This letter emphasizes the potential of chemically modified chitin and chitosan in natural product research. Extracted from crustacean shells, these biopolymers are known for their biocompatibility, biodegradability and non-toxicity. Chemical modifications improve their solubility, adsorption capacity and antimicrobial properties, making them ideal for applications in drug delivery, wound healing and pollutant removal. Furthermore, combining natural products with modified chitosan creates novel therapeutic agents with increased efficacy and fewer side effects. This research highlights the significance of exploring the various applications of chitin and chitosan, aligning with the journal's focus on innovative natural product solutions.