对映选择合成
组合化学
农药
化学
纳米技术
多样性(控制论)
生化工程
有机化学
计算机科学
工程类
材料科学
人工智能
催化作用
生物
生态学
农业
作者
Marina Briand,Elsa Anselmi,Guillaume Dagousset,Emmanuel Magnier
标识
DOI:10.1002/tcr.202300114
摘要
Over the last years, methods devoted to the synthesis of asymmetric molecules bearing a perfluoroalkylated chain have been limited in number. Among them, only a few can be used on a large variety of scaffolds. This microreview aims at summarizing these recent advances in enantioselective perfluoroalkylation (-CF3 , -CF2 H, -Cn F2n+1 ) and highlights the need for new enantioselective methods to easily synthesize chiral fluorinated molecules which would be useful for the pharmaceutical and agrochemical industries. Some perspectives are also mentioned.
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