The article presents an advanced control strategy for cold atom gravimeter, leveraging high-gain observer sliding mode control. This approach involves several key steps: establishing a rigorous active vibration isolation model for cold atomic gravimeters; designing an optimized active vibration isolation system. The high-gain observer of this system effectively mitigates uncertainties associated with internal parameter variations and external ground vibrations. By incorporating fixed disturbances, the observer ensures accurate monitoring of these disturbances. Additionally, a sophisticated high-gain observer sliding mode control law is developed to address the limitations of traditional control methods, which often overlook the stochastic nature and model uncertainties of external disturbances like ground vibrations. This advanced control method rapidly converges the vibration velocity and displacement of the active vibration isolation system of cold atomic gravimeters, significantly enhancing the overall control accuracy of the system.