Implanted Human Cardiac Spheroids Electrically Couple With Infarcted Swine Myocardium

医学
作者
Bijay Guragain,Yuhua Wei,Hanyu Zhang,Asher Kahn-Krell,Lei Ye,Gregory P. Walcott,Jack M. Rogers,Jianyi Zhang
出处
期刊:Circulation [Ovid Technologies (Wolters Kluwer)]
卷期号:149 (23): 1855-1857
标识
DOI:10.1161/circulationaha.123.068568
摘要

HomeCirculationVol. 149, No. 23Implanted Human Cardiac Spheroids Electrically Couple With Infarcted Swine Myocardium No AccessLetterRequest AccessFull TextAboutView Full TextView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toNo AccessLetterRequest AccessFull TextImplanted Human Cardiac Spheroids Electrically Couple With Infarcted Swine Myocardium Bijay Guragain, Yuhua Wei, Hanyu Zhang, Asher Kahn-Krell, Lei Ye, Gregory P. Walcott, Jack M. Rogers and Jianyi (Jay) Zhang Bijay GuragainBijay Guragain https://orcid.org/0000-0002-6859-148X Department of Biomedical Engineering, School of Medicine and School of Engineering.(B.G., Y.W., H.Z., A.K.-K., L.Y., G.P.W., J.M.R., J.Z.). , Yuhua WeiYuhua Wei https://orcid.org/0000-0003-0140-873X Department of Biomedical Engineering, School of Medicine and School of Engineering.(B.G., Y.W., H.Z., A.K.-K., L.Y., G.P.W., J.M.R., J.Z.). , Hanyu ZhangHanyu Zhang https://orcid.org/0000-0003-1810-7677 Department of Biomedical Engineering, School of Medicine and School of Engineering.(B.G., Y.W., H.Z., A.K.-K., L.Y., G.P.W., J.M.R., J.Z.). , Asher Kahn-KrellAsher Kahn-Krell https://orcid.org/0000-0001-7793-3130 Department of Biomedical Engineering, School of Medicine and School of Engineering.(B.G., Y.W., H.Z., A.K.-K., L.Y., G.P.W., J.M.R., J.Z.). , Lei YeLei Ye Department of Biomedical Engineering, School of Medicine and School of Engineering.(B.G., Y.W., H.Z., A.K.-K., L.Y., G.P.W., J.M.R., J.Z.). , Gregory P. WalcottGregory P. Walcott https://orcid.org/0000-0002-9807-7422 Department of Biomedical Engineering, School of Medicine and School of Engineering.(B.G., Y.W., H.Z., A.K.-K., L.Y., G.P.W., J.M.R., J.Z.). Department of Medicine/Cardiovascular Diseases (G.P.W., J.Z), University of Alabama at Birmingham. , Jack M. RogersJack M. Rogers https://orcid.org/0000-0002-3236-4154 Department of Biomedical Engineering, School of Medicine and School of Engineering.(B.G., Y.W., H.Z., A.K.-K., L.Y., G.P.W., J.M.R., J.Z.). and Jianyi (Jay) ZhangJianyi (Jay) Zhang Correspondence to: Jianyi (Jay) Zhang, MD, PhD, Department of Biomedical Engineering, School of Medicine and School of Engineering, The University of Alabama at Birmingham, 1670 University Blvd, Volker Hall G094J, Birmingham, AL 35233. Email E-mail Address: [email protected] Department of Biomedical Engineering, School of Medicine and School of Engineering.(B.G., Y.W., H.Z., A.K.-K., L.Y., G.P.W., J.M.R., J.Z.). Department of Medicine/Cardiovascular Diseases (G.P.W., J.Z), University of Alabama at Birmingham. Originally published3 Jun 2024https://doi.org/10.1161/CIRCULATIONAHA.123.068568Circulation. 2024;149:1855–1857FootnotesFor Sources of Funding and Disclosures, see page 1857.Circulation is available at www.ahajournals.org/journal/circCorrespondence to: Jianyi (Jay) Zhang, MD, PhD, Department of Biomedical Engineering, School of Medicine and School of Engineering, The University of Alabama at Birmingham, 1670 University Blvd, Volker Hall G094J, Birmingham, AL 35233. Email jayzhang@uab.eduReferences1. Pfeffer MA, Braunwald E. Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications.Circulation. 1990; 81:1161–1172. doi: 10.1161/01.cir.81.4.1161LinkGoogle Scholar2. Kawaguchi S, Soma Y, Nakajima K, Kanazawa H, Tohyama S, Tabei R, Hirano A, Handa N, Yamada Y, Okuda S, et al. Intramyocardial transplantation of human iPS cell-derived cardiac spheroids improves cardiac function in heart failure animals.JACC Basic Transl Sci. 2021; 6:239–254. doi: 10.1016/j.jacbts.2020.11.017CrossrefMedlineGoogle Scholar3. Liu YW, Chen B, Yang X, Fugate JA, Kalucki FA, Futakuchi-Tsuchida A, Couture L, Vogel KW, Astley CA, Baldessari A, et al. Human embryonic stem cell-derived cardiomyocytes restore function in infarcted hearts of non-human primates.Nat Biotechnol. 2018; 36:597–605. doi: 10.1038/nbt.4162CrossrefMedlineGoogle Scholar4. Kahn-Krell A, Pretorius D, Ou J, Fast VG, Litovsky S, Berry J, Liu XM, Zhang J. Bioreactor suspension culture: differentiation and production of cardiomyocyte spheroids from human induced pluripotent stem cells.Front Bioeng Biotechnol. 2021; 9:674260. doi: 10.3389/fbioe.2021.674260CrossrefMedlineGoogle Scholar5. Gao L, Gregorich ZR, Zhu W, Mattapally S, Oduk Y, Lou X, Kannappan R, Borovjagin AV, Walcott GP, Pollard AE, et al. Large cardiac muscle patches engineered from human induced-pluripotent stem cell-derived cardiac cells improve recovery from myocardial infarction in swine.Circulation. 2018; 137:1712–1730. doi: 10.1161/CIRCULATIONAHA.117.030785LinkGoogle Scholar eLetters(0)eLetters should relate to an article recently published in the journal and are not a forum for providing unpublished data. Comments are reviewed for appropriate use of tone and language. Comments are not peer-reviewed. Acceptable comments are posted to the journal website only. Comments are not published in an issue and are not indexed in PubMed. Comments should be no longer than 500 words and will only be posted online. References are limited to 10. Authors of the article cited in the comment will be invited to reply, as appropriate.Comments and feedback on AHA/ASA Scientific Statements and Guidelines should be directed to the AHA/ASA Manuscript Oversight Committee via its Correspondence page.Sign In to Submit a Response to This Article Previous Back to top Next FiguresReferencesRelatedDetails June 4, 2024Vol 149, Issue 23 Advertisement Article InformationMetrics © 2024 American Heart Association, Inc.https://doi.org/10.1161/CIRCULATIONAHA.123.068568PMID: 38829934 Originally publishedJune 3, 2024 Keywordshost vs graft reactioninduced pluripotent stem cellsmyocardial infarctionmyocytes, cardiacswinePDF download Advertisement
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