Visible-Light-Induced C—C Bond Cleavage of Dihydroquinazolinones with Trifluoromethyl-Substituted Olefins Defluorinated Alkylation Reactions

The visible-light-induced C-C bond cleavage of dihydroquinazolinone to generate alkyl radicals for defluorinated alkylation reactions with α-trifluoromethyl alkene is reported.The method is featured as transition-metal-free, mild conditions, base-or additive-free, and has a wide range of substrate applicability, which provides a convenient and efficient new method for the synthesis of various alkyl-substituted gem-difluoroalkene.