化学
白磷
烷基
丙酮
光催化
甲苯
磷
表面改性
有机合成
光催化
组合化学
可见光谱
催化作用
溶剂
有机化学
物理
物理化学
光电子学
作者
Fengxiao Wang,Xiyuan Zhang,Jiaming Xu,Shen Qu,Bo Jiang,Zhiwei Miao
标识
DOI:10.1002/adsc.202401355
摘要
Abstract The direct synthesis of organic phosphorus compounds from white phosphorus (P 4 ) is a longstanding challenge in organic synthesis. Here, we present a novel visible light‐induced three‐component functionalization reaction that integrates P 4 , disulfide compounds, and N ‐hydroxyphthalimide (NHPI) esters to produce alkyl‐substituted phosphonodithioates in a one‐pot process. Using 2,4,5,6‐tetrakis(carbazol‐9‐yl)‐1,3‐dicyanobenzene (4CzIPN) as a photocatalyst, blue LEDs (456 nm) as the light source, and N , N ‐diisopropylethylamine (DIPEA) as the reducing agent in an acetone‐toluene solvent system, this method achieves moderate to good yields of structurally diverse phosphonodithioates. The reaction proceeds under mild conditions, ensures complete conversion of P 4 , avoids chlorination, and uses inexpensive, readily available starting materials, offering potential for large‐scale applications.
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