作者
J. Andrew Livingston,Jean‐Yves Blay,Jonathan C. Trent,Claudia Valverde,Mark Agulnik,Mrinal M. Gounder,Axel Le Cesne,Meredith McKean,Michael J. Wagner,Silvia Stacchiotti,Samuel V. Agresta,Alfonso Quintás-Cardama,Sarah Reilly,Kim Coleman Healy,Denice Hickman,Tina Zhao,Alex Ballesteros‐Perez,A.A. Khalil,Michael Collins,Jessica Piel,Kim Horrigan,Ariel Lefkovith,Scott Innis,Alexander J. Lazar,Gregory M. Coté,Andrew J. Wagner
摘要
FHD-609, a potent, selective, heterobifunctional degrader of bromodomain-containing protein 9 (BRD9), was evaluated for treatment of patients with advanced synovial sarcoma (SS) or SMARCB1-deficient tumors.