Electrophoretic deposition of alginate/bioglass composite coating on Mg Ca alloy for degradable metallic implant applications

Surface modifications using bioactive coatings can be utilized effectively to tailor the rate of degradation and enhance biomineralization of magnesium (Mg) alloys. This study examines the effect of alginate/bioglass composite (Alg/BG) coating developed by electrophoretic deposition (EPD) on the biodegradation, bioactivity and biocompatibility of MgCa alloy. Electrochemical corrosion measurement in NaCl solution and in vitro degradation test conducted using simulated body fluid (SBF) revealed that the coated sample has better degradation resistance and bioactivity than bare MgCa alloy. It was noted that the hydrophilic Alg/BG coating enhances biomineralization and promotes in situ deposition of hydroxyapatite on the sample surfaces. The cell culture studies conducted using L929 cells revealed that the coated samples could promote cell adhesion as well as proliferation. Thus, electrophoretic deposition of Alg/BG is suggested as a suitable coating strategy to promote biomineralization and tailor the biodegradation of the MgCa alloy in the physiological environment.