Pharmacokinetic study of PEGylated plasmon resonant gold nanoparticles in tumor-bearing mice

Advances in plasmonic nanoparticle synthesis and functionalization open new possibilities for biomedical applications, including enhanced cancer therapy by selectively gaining access to tumor due to their small size and modifiability. Herein, we report results encompassing the synthesis and PEGylation of gold nanorods and silica/gold nanoshells and an in vivo pharmacokinetics study of functionalized nanoparticles in tumor-bearing mice.