细胞标志蛋白
尼福林
足细胞
医学
肾病
疾病
糖尿病肾病
尿
泌尿系统
膜性肾病
狭缝隔膜
蛋白尿
内科学
生物信息学
肾
内分泌学
糖尿病
生物
作者
Gilbert Akankwasa,Liu Jian-hua,Guixue Cheng,Changjuan An,Xiaosong Qin
出处
期刊:Biomarkers in Medicine
[Future Medicine]
日期:2018-07-06
卷期号:12 (8): 927-935
被引量:27
标识
DOI:10.2217/bmm-2018-0152
摘要
Urinary podocalyxin and nephrin are urine markers of podocyte dysfunction that may reflect the integrity of kidney's filtration barrier. Studies on their respective roles in glomerular diseases are still underway. However, the isolated and unsystematic manner in which they are being studied does not permit proper identification of their roles in each glomerular disease. As such, there is little or no appreciation of what research has already achieved and what remains to be achieved as the research direction is not clearly defined. We explored the recent studies and outlined the major findings regarding the value of both biomarkers in each of the three glomerular disease entities. Our review covered diabetic nephropathy, membranous nephropathy and IgA nephropathy.
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