ANALYSIS OF THE RELATIONSHIP BETWEEN ANXIETYDEPRESSIVE DISORDERS AND PAIN IN PATIENTS WITH MYOFASCIAL SYNDROME

Background. Myofascial syndrome (MFS) as a chronic pain syndrome is most often combined with depressive disorders and can mask hidden «somatization» depressions. Recently, more and more data have been accumulated on the effect of anxiety and depressive manifestations on the course of the pain process, which significantly worsen the prognosis of the disease. Objective: To determine the presence and analyze the relationship between anxiety-depressive disorders and pain in MFS in patients with somatoform autonomic dysfunctions. Material and methods. The study involved 50 patients with somatoform autonomic dysfunctions associated with with MFS as well as anxiety and depressive disorders of varying severity. The pain was studied using the VAS scale, anxiety-depressive disorders were assessed according to HADS. To test the significance of differences in the values of quantitative signs the Kruskal-Wallis H-test was used. The relationship between the signs was assessed using correlation analysis. Differences and associations were considered statistically significant at p<0.05. Results. With an increase in the level of pain, the number of patients with clinical manifestations of anxiety and de- pressive symptoms increases. Correlation analysis of the relationship between pain and depressive disorders (r=0.722, ρ=0.721) as well as between pain and anxiety disorders (r=0.665, ρ=0.618) showed a positive close relationship. Conclusions. Signs of anxiety and depressive disorders varying from subclinical to clinically pronounced forms were detected in 60% of patients. We also established a close relationship between anxiety and depressive disorders, which indicates their comorbidity.