Photocatalyzed gem‐Difluoroallylation of Tertiary Amines with α‐Trifluoromethyl Alkenes

Abstract The gem ‐difluoroalkene moiety has attracted considerable attention from the synthetic chemistry community due to its outstanding performance in the drug design and development. By employing 4‐CzIPN as photocatalyst, a metal‐free synthetic method for gem ‐difluoroalkenes is developed under blue LED irradiation. A wide range of tertiary amines and α‐trifluoromethyl alkenes are applicable in the present gem ‐difluoroallylation and successfully transformed into the gem ‐difluoroalkenes in good yields.