Assessment of Accuracy and Precision of Quantification of Ultra-Widefield Images

Advances in ultra-widefield (UWF) imaging technology have allowed noninvasive images of the peripheral retina. However, UWF images inherently include significant distortion when projected onto a 2-dimensional surface for viewing, which presents a significant challenge for obtaining quantitative measurements. In montaged UWF images, area measurements will have an error of ≤5-fold if one assumes each pixel to have equal size on the retina.1 Therefore, techniques to address the effect of this distortion are crucial to fully utilize its clinical information.