Intracranial metastases from unsuspected choriocarcinoma

Choriocarcinoma, a tumor with frequent cerebral metastasis, is common in Thailand. Three cases are reported of unsuspected choriocarcinoma presenting with the symptoms of cerebrovascular disorders. The cerebral lesions are likely to be associated with the capability of tumor cells for vascular invasion, embolization, and occlusion. Metastatic choriocarcinoma of the brain should be suspected in women, especially if Oriental, presenting with symptoms and signs of cerebrovascular disorders and a history of previous pregnancy. The diagnosis is established by a rising chorionic gonadotropin titer and/or identification of tumor cells.