Designing and implementing a comparative effectiveness study of two strategies for delivering high quality CHD prevention: Methods and participant characteristics for the Heart to Health study

医学 弗雷明翰风险评分 随机对照试验 物理疗法 随机化 研究设计 家庭医学 疾病 老年学 内科学 社会科学 社会学
作者
Stacey Sheridan,Lindy B. Draeger,Michael Pignone,Philip D. Sloane,Carmen D. Samuel‐Hodge,Eric Finkelstein,Ziya Gizlice,Maihan B. Vu,Daniel P. Gitterman,Shrikant I. Bangdiwala,Katrina E Donahue,Kelly R. Evenson,Alice S. Ammerman,Thomas C. Keyserling
出处
期刊:Contemporary Clinical Trials [Elsevier BV]
卷期号:36 (2): 394-405 被引量:16
标识
DOI:10.1016/j.cct.2013.07.013
摘要

Although lifestyle and medications are effective for coronary heart disease (CHD) risk reduction, few studies have examined the comparative effectiveness of various strategies for delivering high quality CHD risk reduction. In this paper, we report on the design and baseline characteristics of participants for just such a trial. We conducted a randomized trial of the same lifestyle and medication intervention delivered in two alternate formats: counselor-delivered or web-based. The trial was conducted at 5 diverse practices in a family medicine research network and included men and women age 35–79 who were at high risk of CHD events based on 10-year predicted Framingham risk of ≥ 10% or a known history of cardiovascular disease. After individual-level randomization, participants in both arms received a decision aid plus four intensive intervention visits and 3 maintenance visits over 12 months. The primary outcome was change in 10-year predicted CHD risk among patients without prior cardiovascular disease. Secondary outcomes, measured among all participants, included changes in CHD risk factors, cost-effectiveness, and acceptability at 4 and 12-month follow-up. We randomized 489 eligible patients: 389 without and 100 with a known history of cardiovascular disease. Mean age was 62.3. 75% were white, 25% African-American. 45% had a college education. 88% had health insurance. Mean 10-year predicted CHD risk was 16.9%. We have successfully recruited a diverse sample of practices and patients that will provide a rich sample in which to test the comparative effectiveness of two strategies to implement high quality CHD prevention.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
傻傻的凤灵应助元气糖采纳,获得10
1秒前
kyt666完成签到,获得积分10
1秒前
1秒前
1秒前
wang完成签到,获得积分10
1秒前
2秒前
XS_QI发布了新的文献求助10
2秒前
3秒前
壮观的沉鱼完成签到 ,获得积分20
3秒前
发阿发完成签到,获得积分10
3秒前
英俊的铭应助既晓采纳,获得10
4秒前
5秒前
pauline完成签到,获得积分10
5秒前
5秒前
5秒前
核桃发布了新的文献求助10
6秒前
fsy完成签到,获得积分10
7秒前
2947292085完成签到,获得积分10
7秒前
XYX发布了新的文献求助10
7秒前
怡然云朵发布了新的文献求助10
8秒前
日常卖命发布了新的文献求助10
8秒前
ssss发布了新的文献求助10
8秒前
傻傻的凤灵应助XS_QI采纳,获得10
9秒前
huohuo完成签到,获得积分10
10秒前
WangXinkui发布了新的文献求助10
11秒前
看文献的高光谱完成签到,获得积分10
11秒前
番茄炒西红柿完成签到,获得积分10
11秒前
荣和发布了新的文献求助10
11秒前
11秒前
慕青应助陈晓迪1992采纳,获得10
12秒前
12秒前
12秒前
12秒前
13秒前
14秒前
14秒前
Esten发布了新的文献求助10
15秒前
AHA完成签到,获得积分10
15秒前
dtf完成签到,获得积分10
16秒前
高分求助中
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
A new approach to the extrapolation of accelerated life test data 1000
Indomethacinのヒトにおける経皮吸収 400
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 370
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
Aktuelle Entwicklungen in der linguistischen Forschung 300
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3991374
求助须知:如何正确求助?哪些是违规求助? 3532683
关于积分的说明 11258355
捐赠科研通 3271693
什么是DOI,文献DOI怎么找? 1805506
邀请新用户注册赠送积分活动 882503
科研通“疑难数据库(出版商)”最低求助积分说明 809319