滋养层
螺旋动脉
怀孕
胎儿
巨噬细胞
蜕膜
血管生成
免疫学
胎盘
生物
人口
医学
细胞生物学
癌症研究
体外
遗传学
环境卫生
生物化学
作者
Jinli Ding,Tailang Yi,Jing Yang
出处
期刊:Chin J Reprod Contracep
日期:2017-11-25
卷期号:37 (11): 938-941
标识
DOI:10.3760/cma.j.issn.2096-2916.2017.11.016
摘要
Macrophages are the second most abundant leukocyte population at the fetal-maternal interface, which perform many specific functions including host defense, angiogenesis, immunological regulation, and tissue development. Aberrantly activated uterine macrophages can affect trophoblast function and placental development, which may result in various adverse pregnancy outcomes, including pre-eclampsia and premature labor. In this review, we will focus on the characteristic of macrophages at the fetal-maternal interface, and those roles in normal and pathological pregnancy.
Key words:
Decidual macrophages; Pregnancy; Trophoblast; Spiral artery remodeling
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