Synthesis of N‐Sulfonyl Pyrazoles Through Cyclization Reactions of Sulfonyl Hydrazines with Enaminones Promoted by p‐TSA

A strategy for the rapid synthesis of 3‐substituted N ‐sulfonyl pyrazoles via p ‐TSA‐promoted cyclization reactions of sulfonyl hydrazines with N , N ‐dimethyl enaminones has been developed. This method achieves both the formation of pyrazole ring and the continued retention of sulfonyl group, providing a series of 3‐substituted N ‐sulfonyl pyrazoles in moderate to good yields with good functional group tolerance, easily available starting materials, and can be scaled‐up.