The effect of atropine 0.01% eyedrops on relative peripheral refraction in myopic children

睫状肌麻痹 阿托品 安慰剂 医学 折射误差 眼科 麻醉 外围设备 眼病 内科学 病理 替代医学
作者
Jiaxin Tian,Shifei Wei,Shi‐Ming Li,Wen An,Weiling Bai,Xintong Liang,Jiang Du,Ning Li Wang
出处
期刊:Eye [Springer Nature]
卷期号:37 (2): 356-361 被引量:5
标识
DOI:10.1038/s41433-021-01923-1
摘要

Relative peripheral refraction (RPR) is a significant factor that participates in myopic development. Here, we evaluated the effects of atropine 0.01% eyedrops, as an antimyopia drug, on RPR.Seventy-three children were enrolled from a randomized, double-blinded, placebo-0.01% atropine eyedrops cross-over trial. The study group had used the placebo for one year and then crossed over to atropine 0.01% eyedrops for half a year. The control group had used 0.01% atropine for one year and then crossed over to placebo eyedrops for half a year. Central and horizontal peripheral refractions (15° and 30° at the temporal and nasal retina) were measured under non-cycloplegia and cycloplegia.No significant differences in age, gender, and central refraction were identified between the two groups (P > 0.05). Under non-cycloplegia, the control group showed significant relative hyperopia in the temporal 30° retina and the nasal retina (P = 0.031; P < 0.001; P < 0.001). In the study group, the relative hyperopia in the temporal 30° retina disappeared (P = 0.983). After cycloplegia, the control group had less myopia in central refractions and less hyperopia in temporal RPR (P < 0.001; P = 0.039; P < 0.001). The study group did not present significant changes in central refractions and temporal RPR (P = 0.122; P = 0.222; P = 0.475).For myopic children, atropine 0.01% eyedrops can alleviate relative hyperopia in the temporal retina and the hyperopic shift before cycloplegia. The effect might participate in myopia control.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
REN发布了新的文献求助10
1秒前
谨言完成签到 ,获得积分10
1秒前
Akim应助Ma采纳,获得10
2秒前
zdd发布了新的文献求助10
2秒前
西红柿呀完成签到,获得积分10
2秒前
3秒前
3秒前
靓丽行天完成签到,获得积分10
3秒前
崔尔蓉完成签到,获得积分10
4秒前
玉玉完成签到,获得积分10
4秒前
不羁完成签到 ,获得积分10
4秒前
4秒前
LM完成签到,获得积分10
5秒前
En完成签到,获得积分0
5秒前
爱情哈尔完成签到,获得积分10
5秒前
5秒前
lalkiii完成签到,获得积分10
5秒前
unflycn完成签到,获得积分10
5秒前
5秒前
wyn完成签到,获得积分10
6秒前
6秒前
hhhhhhhhhh完成签到 ,获得积分10
6秒前
lm完成签到 ,获得积分10
6秒前
fuyuhaoy完成签到,获得积分10
6秒前
wanci应助majf采纳,获得10
6秒前
冲天小猪完成签到,获得积分10
7秒前
7秒前
章鱼哥完成签到,获得积分10
7秒前
8秒前
9秒前
悦耳寒云发布了新的文献求助10
10秒前
Chaiyuan完成签到 ,获得积分10
10秒前
10秒前
曾经青亦发布了新的文献求助10
10秒前
Aprial完成签到,获得积分10
11秒前
12秒前
cc发布了新的文献求助10
12秒前
ziyu完成签到,获得积分10
12秒前
尹山蝶完成签到,获得积分10
13秒前
ll应助JJ采纳,获得10
13秒前
高分求助中
Nickel, Cobalt and Palladium Catalysed Infarction with Ventricular following rich structural diversity 1000
A new approach to the extrapolation of accelerated life test data 1000
Cognitive Neuroscience: The Biology of the Mind 1000
Technical Brochure TB 814: LPIT applications in HV gas insulated switchgear 1000
Immigrant Incorporation in East Asian Democracies 600
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3968608
求助须知:如何正确求助?哪些是违规求助? 3513486
关于积分的说明 11168243
捐赠科研通 3248926
什么是DOI,文献DOI怎么找? 1794540
邀请新用户注册赠送积分活动 875188
科研通“疑难数据库(出版商)”最低求助积分说明 804676