Effect of hyperthermic intraperitoneal chemotherapy(HIPEC) combined with cytoreductive surgery(CRS) on prognosis in colorectal cancer patients with peritoneal metastasis: a systematic review and meta-analysis

divided the experimental groups into OPEN group and CLOSE group according to the different HIPEC devices.In the OPEN group, The results showed that the OS of THE CRS and HIPEC groups was higher than that in the control group; In the CLOSE group, the experimental group OS was higher.OPEN group showed lower heterogeneity.Divided into different subgroups according to the duration of HIPEC treatment, 30min group and 60-100min group showed that the OS of CRS and HIPEC groups was higher than that of the control group, and there was low heterogeneity in the 60-100min group.Sensitivity analysis: Sensitivity analysis showed that there was no significant difference in the results of the combined analysis after each study was deleted, indicating that the results of the combined analysis were more reliable.Country(ies) involved: China.