主旨
医学
放射科
间质瘤
内镜超声
正电子发射断层摄影术
磁共振成像
阶段(地层学)
甲磺酸伊马替尼
医学影像学
伊马替尼
病理
间质细胞
内科学
古生物学
生物
髓系白血病
作者
Moriz Herzberg,Meinrad Beer,Sudha A. Anupindi,Kurt Vollert,Thomas Kröncke
标识
DOI:10.1016/j.jpedsurg.2018.03.022
摘要
Gastrointestinal stromal tumors (GIST) are extremely rare in children. Imaging plays a key role in staging and monitoring therapy (surgical and with tyrosine kinase inhibitors). The vast majority of articles addressing imaging of GIST base on adults and are based on CT. The subtype "pediatric GIST" - if at all - is only mentioned in a dependent clause. Although the imaging features in children and adults are similar, histology, clinical course and thus imaging approach are different.A PubMed search using the search terms "Gastrointestinal stromal tumor, GIST, WT GIST, children, pediatric, carney's triad, imaging, staging, follow-up, MRI, CEUS, ultrasonography, Positron emission tomography" was conducted. Studies that reported on laparoscopy, endoscopy and surgical techniques only were excluded.Based on our selective literature review, we present alternative radiological imaging strategies using MRI, contrast enhanced ultrasound (CEUS) and PET-CT to stage and follow-up pediatric GIST patients. As pediatric GIST often is a chronic disease, minimizing exposure to ionizing radiation is mandatory.MRI, contrast enhanced ultrasound and PET-CT instead of CT are the imaging modalities to evaluate pediatric GIST.Systematic review LEVEL OF EVIDENCE: III.
科研通智能强力驱动
Strongly Powered by AbleSci AI