自愈水凝胶
氢键
材料科学
单体
傅里叶变换红外光谱
自愈
高分子化学
聚合物
肿胀 的
超分子聚合物
流变学
酰胺
聚酰胺
化学工程
化学
复合材料
有机化学
分子
替代医学
病理
工程类
医学
作者
Yalei Ren,Yinyu Zhang,Wenhui Sun,Fei Gao,Weigui Fu,Peiyi Wu,Wenguang Liu
出处
期刊:Polymer
[Elsevier]
日期:2017-09-01
卷期号:126: 1-8
被引量:39
标识
DOI:10.1016/j.polymer.2017.08.016
摘要
Poly(N-acryloyl glycinamide) (PNAGA) with a protein-like thermoresponsive gelation behavior in water has been developed as a high strength self-healable supramolecular polymer(SP) hydrogels recently. However, harsh conditions, such as high temperature treatment and long waiting time, were required for achieving the complete healing due to strong dual amide hydrogen bonding interactions. In this study, to create an autonomic rapid self-healing SP hydrogel, we deliberately introduced a methyl into the opposite side to dual amide to synthesize N-methacryloyl glycinamide (MNAGA) monomer. Rheological analysis, dynamic light scattering(DLS), Fourier transform infrared (FTIR) spectroscopy, and Gaussian calculation revealed that one substitution methyl caused a considerable perturbation to the hydrogen bonding interaction, thus leading to the increased starting gelling concentration and pronounced decrease in mechanical properties of PMNAGA hydrogel compared to PNAGA hydrogel. The PMNAGA hydrogel was shown to exhibit rapid autonomic reparability without any external intervention, and dynamic swelling measurement indicated this PMNAGA hydrogel could evolve from permanent to transient network due to the metastable hydrogen bonding crosslinkage, depending on its environmental temperature. This intriguing robust, autonomous healing and autolytic PMNAGA hydrogel holds great potential as a short-term embolic agent for blocking blood vessel and artificial tears for moistening eyes.
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