Quality assessment of crude and processed Arecae semen based on colorimeter and HPLC combined with chemometrics methods

Journal of Separation ScienceVolume 40, Issue 10 p. 2151-2160 RESEARCH ARTICLE Quality assessment of crude and processed Arecae semen based on colorimeter and HPLC combined with chemometrics methods Meng Sun, Corresponding Author Meng Sun 284778715@qq.com orcid.org/0000-0002-8715-0719 Department of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China The Key Unit of Chinese Medicine Digitalization Quality Evaluation of State Administration of Traditional Chinese Medicine, Guangzhou, China The Research Center for Quality Engineering Technology of Traditional Chinese Medicine at Guangdong Universities, Guangzhou, China These authors contributed equally to this work. Correspondence Miss Meng Sun, Department of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China. Email: 284778715@qq.comSearch for more papers by this authorDonghui Yan, Donghui Yan Department of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China The Key Unit of Chinese Medicine Digitalization Quality Evaluation of State Administration of Traditional Chinese Medicine, Guangzhou, China The Research Center for Quality Engineering Technology of Traditional Chinese Medicine at Guangdong Universities, Guangzhou, China These authors contributed equally to this work.Search for more papers by this authorXiaolu Yang, Xiaolu Yang Department of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China The Key Unit of Chinese Medicine Digitalization Quality Evaluation of State Administration of Traditional Chinese Medicine, Guangzhou, China The Research Center for Quality Engineering Technology of Traditional Chinese Medicine at Guangdong Universities, Guangzhou, ChinaSearch for more papers by this authorXingyang Xue, Xingyang Xue Guangzhou Medical University Cancer Hospital and Institute, Guangzhou, Guangdong, ChinaSearch for more papers by this authorSujuan Zhou, Sujuan Zhou College of Medical Information Engineering, Guangdong Pharmaceutical University, Guangzhou, ChinaSearch for more papers by this authorShengwang Liang, Shengwang Liang Department of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China The Key Unit of Chinese Medicine Digitalization Quality Evaluation of State Administration of Traditional Chinese Medicine, Guangzhou, China The Research Center for Quality Engineering Technology of Traditional Chinese Medicine at Guangdong Universities, Guangzhou, ChinaSearch for more papers by this authorShumei Wang, Shumei Wang Department of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China The Key Unit of Chinese Medicine Digitalization Quality Evaluation of State Administration of Traditional Chinese Medicine, Guangzhou, China The Research Center for Quality Engineering Technology of Traditional Chinese Medicine at Guangdong Universities, Guangzhou, China Additional corresponding authors Prof. Jiang Meng Email: jiangmeng666@126.com; Prof. Shumei Wang Email: 2395903468@qq.comSearch for more papers by this authorJiang Meng, Jiang Meng Department of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China The Key Unit of Chinese Medicine Digitalization Quality Evaluation of State Administration of Traditional Chinese Medicine, Guangzhou, China The Research Center for Quality Engineering Technology of Traditional Chinese Medicine at Guangdong Universities, Guangzhou, China Additional corresponding authors Prof. Jiang Meng Email: jiangmeng666@126.com; Prof. Shumei Wang Email: 2395903468@qq.comSearch for more papers by this author Meng Sun, Corresponding Author Meng Sun 284778715@qq.com orcid.org/0000-0002-8715-0719 Department of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China The Key Unit of Chinese Medicine Digitalization Quality Evaluation of State Administration of Traditional Chinese Medicine, Guangzhou, China The Research Center for Quality Engineering Technology of Traditional Chinese Medicine at Guangdong Universities, Guangzhou, China These authors contributed equally to this work. Correspondence Miss Meng Sun, Department of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China. Email: 284778715@qq.comSearch for more papers by this authorDonghui Yan, Donghui Yan Department of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China The Key Unit of Chinese Medicine Digitalization Quality Evaluation of State Administration of Traditional Chinese Medicine, Guangzhou, China The Research Center for Quality Engineering Technology of Traditional Chinese Medicine at Guangdong Universities, Guangzhou, China These authors contributed equally to this work.Search for more papers by this authorXiaolu Yang, Xiaolu Yang Department of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China The Key Unit of Chinese Medicine Digitalization Quality Evaluation of State Administration of Traditional Chinese Medicine, Guangzhou, China The Research Center for Quality Engineering Technology of Traditional Chinese Medicine at Guangdong Universities, Guangzhou, ChinaSearch for more papers by this authorXingyang Xue, Xingyang Xue Guangzhou Medical University Cancer Hospital and Institute, Guangzhou, Guangdong, ChinaSearch for more papers by this authorSujuan Zhou, Sujuan Zhou College of Medical Information Engineering, Guangdong Pharmaceutical University, Guangzhou, ChinaSearch for more papers by this authorShengwang Liang, Shengwang Liang Department of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China The Key Unit of Chinese Medicine Digitalization Quality Evaluation of State Administration of Traditional Chinese Medicine, Guangzhou, China The Research Center for Quality Engineering Technology of Traditional Chinese Medicine at Guangdong Universities, Guangzhou, ChinaSearch for more papers by this authorShumei Wang, Shumei Wang Department of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China The Key Unit of Chinese Medicine Digitalization Quality Evaluation of State Administration of Traditional Chinese Medicine, Guangzhou, China The Research Center for Quality Engineering Technology of Traditional Chinese Medicine at Guangdong Universities, Guangzhou, China Additional corresponding authors Prof. Jiang Meng Email: jiangmeng666@126.com; Prof. Shumei Wang Email: 2395903468@qq.comSearch for more papers by this authorJiang Meng, Jiang Meng Department of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China The Key Unit of Chinese Medicine Digitalization Quality Evaluation of State Administration of Traditional Chinese Medicine, Guangzhou, China The Research Center for Quality Engineering Technology of Traditional Chinese Medicine at Guangdong Universities, Guangzhou, China Additional corresponding authors Prof. Jiang Meng Email: jiangmeng666@126.com; Prof. Shumei Wang Email: 2395903468@qq.comSearch for more papers by this author First published: 29 March 2017 https://doi.org/10.1002/jssc.201700006Citations: 17 Conflict of interest: The authors have declared no conflict of interest. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Abstract Raw Arecae Semen, the seed of Areca catechu L., as well as Arecae Semen Tostum and Arecae semen carbonisata are traditionally processed by stir-baking for subsequent use in a variety of clinical applications. These three Arecae semen types, important Chinese herbal drugs, have been used in China and other Asian countries for thousands of years. In this study, the sensory technologies of a colorimeter and sensitive validated high-performance liquid chromatography with diode array detection were employed to discriminate raw Arecae semen and its processed drugs. The color parameters of the samples were determined by a colorimeter instrument CR-410. Moreover, the fingerprints of the four alkaloids of arecaidine, guvacine, arecoline and guvacoline were surveyed by high-performance liquid chromatography. Subsequently, Student's t test, the analysis of variance, fingerprint similarity analysis, hierarchical cluster analysis, principal component analysis, factor analysis and Pearson's correlation test were performed for final data analysis. The results obtained demonstrated a significant color change characteristic for components in raw Arecae semen and its processed drugs. Crude and processed Arecae semen could be determined based on colorimetry and high-performance liquid chromatography with a diode array detector coupled with chemometrics methods for a comprehensive quality evaluation. Citing Literature Volume40, Issue10May 2017Pages 2151-2160 RelatedInformation