Meandering main pancreatic duct is an uncommon anatomical variation of main pancreatic duct characterized by abnormal curvature of the main pancreatic duct in pancreatic head. It comprises of two types (loop type and reverse Z-type) and can be underlying cause for idiopathic recurrent acute pancreatitis. We report a case of Meandering Main pancreatic duct in a 26-year-old female who presented with multiple episodes of idiopathic recurrent acute pancreatitis.