作者
Kazuo Tsubota,Norihiko Yokoi,Jun Shimazaki,Hitoshi Watanabe,Murat Doğru,Masakazu Yamada,Shigeru Kinoshita,Hyo-Myung Kim,Hung-Won Tchah,Joon Young Hyon,Kyung Chul Yoon,Kyoung Yul Seo,Xuguang Sun,Wei Chen,Lingyi Liang,Mingwu Li,Lei Zhu,Lei Zhu,Xuguang Sun,Wei Chen,Yingping Deng,Jing Hong,Ying Jie,Mingwu Li,Ying Li,Lingyi Liang,Hong Qi,Hua Wang,Xiaoming Yan,Jing Wang,Yufeng Ye,Jin Yuan,Hong Zhang,Hui Zhan,Mingchang Zhang,Shaozhen Zhao,Hyo-Myung Kim,Hungwon Tchah,Chul Young Choi,Eui‐Sang Chung,Joon Young Hyon,Hyun Seung Kim,Mee Kum Kim,Myoung-Joon,Tae‐im Kim,Do‐Hyung Lee,Hyung Keun Lee,Kyoung Yul Seo,Jong Suk Song,Kyung Chul Yoon,Kazuo Tsubota,Norihiko Yokoi,Shiro Amano,Reiko Arita,Murat Doğru,Yuichi Hori,Tetsuya Kawakita,Motoko Kawashima,Shizuka Koh,Kohji Nishida,Yoko Ogawa,Jun Shimazaki,Hitoshi Watanabe,Masakazu Yamada,Masahiko Yamaguchi
摘要
For the last 20 years, a great amount of evidence has accumulated through epidemiological studies that most of the dry eye disease encountered in daily life, especially in video display terminal (VDT) workers, involves short tear film breakup time (TFBUT) type dry eye, a category characterized by severe symptoms but minimal clinical signs other than short TFBUT. An unstable tear film also affects the visual function, possibly due to the increase of higher order aberrations. Based on the change in the understanding of the types, symptoms, and signs of dry eye disease, the Asia Dry Eye Society agreed to the following definition of dry eye: “Dry eye is a multifactorial disease characterized by unstable tear film causing a variety of symptoms and/or visual impairment, potentially accompanied by ocular surface damage.” The definition stresses instability of the tear film as well as the importance of visual impairment, highlighting an essential role for TFBUT assessment. This paper discusses the concept of Tear Film Oriented Therapy (TFOT), which evolved from the definition of dry eye, emphasizing the importance of a stable tear film.