Protocatechuic acid grafted chitosan/oxidized glucomannan hydrogel with antimicrobial and anti-inflammatory effects for enhancing wound repair

Oxidative stress, inflammation, and bacterial infection are critical barriers to wound healing. In this work, a composite wound dressing was designed to promote wound healing and reduce complications. A hydrogel with antibacterial, anti-inflammatory, and antioxidant properties was prepared by crosslinking chitosan (CS) and oxidized konjac glucomannan with Mg