中性粒细胞胞外陷阱
存水弯(水管)
细胞外
化学
控制(管理)
细胞生物学
生物
物理
炎症
计算机科学
免疫学
人工智能
气象学
作者
Mariano Malamud,Lauren Whitehead,Alasdair McIntosh,Fabio Colella,Anke J. Roelofs,Takato Kusakabe,Ivy M. Dambuza,Annie Phillips-Brookes,Fabián Salazar,Federico M. Perez,Romey Shoesmith,Przemysław Zakrzewski,Emily A. Sey,Cecília Rodrigues,Petruta L. Morvay,Pierre Redelinghuys,Tina Bedekovic,Maria J. Fernandes,Ruqayyah J. Almizraq,Donald R. Branch
出处
期刊:Nature
[Springer Nature]
日期:2024-08-14
卷期号:633 (8029): 442-450
被引量:31
标识
DOI:10.1038/s41586-024-07820-3
摘要
Regulation of neutrophil activation is critical for disease control. Neutrophil extracellular traps (NETs), which are web-like structures composed of DNA and neutrophil-derived proteins, are formed following pro-inflammatory signals; however, if this process is uncontrolled, NETs contribute to disease pathogenesis, exacerbating inflammation and host tissue damage
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