Microfluidic Devices as Miniaturized Diagnostics for Gynecological Cancers

Gynecological cancers, including cervical, endometrial, and ovarian cancers, contribute to a significant portion of female cancer-related deaths. Despite advancements in cancer detection, these diseases continue to pose challenges due to late-stage diagnoses and limited cost-effective screening methods. This review focuses on the utilization of microfluidic devices (MFD) as an alternative and cost-effective tool for diagnosing and screening gynecological cancers. MFD are portable instruments capable of biomarkers separation, extraction, dilution, mixing and detection. Their compact size and efficiency make them advantageous for comprehensive sample analysis. The emergence of microfluidic point-of-care devices offers potential for identifying new cancer biomarkers and facilitating early detection. This review on the utilization of MFD in gynecological cancer research summarizes literature between 2006-2023.