An insight into bisphenol A, food exposure and its adverse effects on health: A review

双酚A 内分泌系统 化学 环境化学 毒理 激素 医学 生物 内分泌学 环氧树脂 有机化学
作者
Muhammad Faisal Manzoor,Tayyaba Tariq,Birjees Fatima,Amna Sahar,Farwa Tariq,Seemal Munir,Sipper Khan,Muhammad Modassar Ali Nawaz Ranjha,Aysha Sameen,Xin‐An Zeng,Salam A. Ibrahim
出处
期刊:Frontiers in Nutrition [Frontiers Media SA]
卷期号:9 被引量:87
标识
DOI:10.3389/fnut.2022.1047827
摘要

Bisphenol A (BPA) is a synthetic chemical widely employed to synthesize epoxy resins, polymer materials, and polycarbonate plastics. BPA is abundant in the environment, i.e., in food containers, water bottles, thermal papers, toys, medical devices, etc., and is incorporated into soil/water through leaching. Being a potent endocrine disrupter, and has the potential to alter several body mechanisms. Studies confirmed its anti-androgen action and estrogen-like effects, which impart many negative health impacts, especially on the immune system, neuroendocrine process, and reproductive mechanism. Moreover, it can also induce mutagenesis and carcinogenesis, as per recent scientific research. This review focuses on BPA's presence and concentrations in different environments, food sources and the basic mechanisms of BPA-induced toxicity and health disruptions. It is a unique review of its type because it focuses on the association of cancer, hormonal disruption, immunosuppression, and infertility with BPA. These issues are widespread today, and BPA significantly contributes to their incidence because of its wide usage in daily life utensils and other accessories. The review also discusses researched-based measures to cope with the toxic chemical.

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