医学
酒精性肝病
肝病
公共卫生
限制
环境卫生
酒
肝硬化
人口
疾病
酒精性肝炎
重症监护医学
内科学
病理
生物化学
化学
机械工程
工程类
作者
Robyn Burton,Lorenzo Leggio,Alexandre Louvet,Nick Sheron,Ashwani K. Singal
标识
DOI:10.14309/ajg.0000000000003427
摘要
Alcohol-associated liver disease (ALD) is the leading cause of morbidity, disease adjusted life-years lost, and mortality worldwide. The significant burden and cost to the healthcare systems from ALD is largely preventable, given that alcohol use is the most important determinant of risk and severity of ALD. In this article, we will review the emerging evidence for public health policies (minimum unit price of alcohol, limiting or banning alcohol advertising), aiming to reduce the availability of alcohol at the population level (primary prevention), preventing ALD especially advanced form of cirrhosis in at risk individuals (secondary prevention), and improving liver outcomes and long-term survival in patients with advanced ALD of cirrhosis and / or alcohol-associated hepatitis (tertiary prevention). We will highlight the critical role of clinicians in promoting the public health policies, widespread screening for AUD and for ALD, and integrating liver with addiction care for patients with ALD.
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