Anisotropic Nanoparticle Arrays Guided by Ordered Nanowire Films Enhance Surface‐Enhanced Raman Scattering

Abstract Designing high‐efficiency surface‐enhanced Raman scattering (SERS) substrates has attracted explosive attention in recent decades for their novel and potential applications. Great achievements have been made to optimize the intrinsic activity of nanomaterial in SERS substrates, while little attention has been paid to the unique structural design of the nanomaterial building blocks. Herein, a new strategy is provided for assembling Au nanoparticles into well‐defined ordered structures by using a highly ordered arrangement nanowires template to explore the ordering effect on the SERS performance. The highly ordered Au nanoparticle arrays show a detection limit of 10 −9 m that exceeds disordered Au particles by two orders of magnitude, as well as over treble enhancement factor at the same detection concentration. Importantly, this novel scientific discovery can be further confirmed in various probed molecules or nanoparticles with different diameters, which means SERS substrate design can be pushed forward further combined with traditional intrinsic activity design.