The pressure time integral: An underused, clinically significant parameter as a determinant of neuropathic ulceration in diabetes

前脚 医学 糖尿病 周围神经病变 赤脚的 步态 外围设备 外科 物理医学与康复 内科学 并发症 内分泌学
作者
Erica Bartolo,Claudia Giacomozzi,David Coppini,Alfred Gatt
出处
期刊:Gait & Posture [Elsevier BV]
卷期号:100: 210-215 被引量:4
标识
DOI:10.1016/j.gaitpost.2022.12.018
摘要

The purpose of this study was to evaluate plantar pressure dynamics in the occurrence of active diabetic neuropathic ulceration (DNU) and any changes in loadings occurring in individuals with a history of diabetic neuropathic ulceration (DHNU). Since current gold standard offloading strategies are not producing desirable healing outcomes and optimum ulcer prevention, this study aimed to better understand the effect of diabetic peripheral neuropathy (DPN) and ulceration on mean peak plantar pressure (MPPP) and pressure-time integral (PTI) changes.Is there a redistribution of plantar pressure during gait in the presence of active and history of diabetic neuropathic ulceration?A prospective, cross-sectional study was conducted, in which, eighty adult participants were divided into four groups, namely, the DM, DPN, DNU and DHNU groups. Participants were instructed to walk barefoot over a Tekscan HR Mat™ at self-selected speed. MPPP and PTI data were analysed under five forefoot anatomical landmarks and compared between individuals with and without active neuropathic ulceration.Minimal MPPP significant changes were observed between ulcerated and non-ulcerated groups, however, PTI values were significantly increased in the ulcerated groups under all plantar ulceration regions. No significant plantar pressure differences were observed between the DNU and DHNU groups. Logistic regression tests demonstrated that as PTIs under the hallux increase, the likelihood of an individual living with DPN developing ulceration increases.A significant increase in PTI values in the presence of ulceration highlights the importance of evaluating the duration of loads under forefoot regions during gait rather than just focusing on the magnitude of pressures during ulcer management and prevention. Moreover, results show that PTI values remain high in the presence of a history of neuropathic ulceration, possibly demonstrating the value of PTI as a clinical tool over MPPP in the assessment of the high-risk diabetic foot.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
是莉莉娅发布了新的文献求助10
1秒前
2秒前
2秒前
暴富完成签到,获得积分10
2秒前
孙琴琴完成签到,获得积分10
2秒前
超级馒头完成签到,获得积分10
2秒前
2秒前
在水一方应助胡航航采纳,获得10
2秒前
嗑盐废物完成签到,获得积分10
2秒前
温婉的乞发布了新的文献求助10
3秒前
QJH发布了新的文献求助10
3秒前
顾矜应助星月采纳,获得10
3秒前
魔幻傲霜完成签到,获得积分10
4秒前
樘樘发布了新的文献求助10
4秒前
紫色de泡沫完成签到,获得积分10
4秒前
4秒前
slby完成签到 ,获得积分10
4秒前
简单宛秋完成签到,获得积分10
4秒前
5秒前
5秒前
5秒前
6秒前
感动的紊发布了新的文献求助10
7秒前
神马都不懂完成签到,获得积分10
7秒前
liu完成签到 ,获得积分10
7秒前
香蕉觅云应助朴实的小萱采纳,获得10
7秒前
galaxy发布了新的文献求助10
7秒前
暮凝发布了新的文献求助10
7秒前
佳佳应助繁多星采纳,获得10
7秒前
认真的傲柏完成签到,获得积分10
7秒前
共享精神应助asdfghjkl采纳,获得10
8秒前
9秒前
9秒前
樘樘完成签到,获得积分10
9秒前
ding应助惠惠采纳,获得10
10秒前
徐徐完成签到,获得积分10
10秒前
不期而遇0811完成签到,获得积分20
10秒前
10秒前
11秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Technical Brochure TB 814: LPIT applications in HV gas insulated switchgear 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Picture Books with Same-sex Parented Families: Unintentional Censorship 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
A Preliminary Study on Correlation Between Independent Components of Facial Thermal Images and Subjective Assessment of Chronic Stress 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3970394
求助须知:如何正确求助?哪些是违规求助? 3515139
关于积分的说明 11177107
捐赠科研通 3250335
什么是DOI,文献DOI怎么找? 1795254
邀请新用户注册赠送积分活动 875732
科研通“疑难数据库(出版商)”最低求助积分说明 805054