Relative rates of cancers and deaths in Australian communities with PFAS environmental contamination associated with firefighting foams: A cohort study using linked data

医学 环境卫生 队列 消防 污染 队列研究 生态学 内科学 地理 地图学 生物
作者
HD Law,Bruce K. Armstrong,Catherine D’Este,Rose Hosking,Kayla Smurthwaite,Susan Trevenar,Robyn Lucas,Nina Lazarevic,MD Kirk,Rosemary Korda
出处
期刊:Cancer Epidemiology [Elsevier BV]
卷期号:82: 102296-102296 被引量:6
标识
DOI:10.1016/j.canep.2022.102296
摘要

Per- and polyfluoroalkyl substances (PFAS) are environmental contaminants that are potentially harmful to health. We examined if rates of selected cancers and causes of deaths were elevated in three Australian communities with local environmental contamination caused by firefighting foams containing PFAS. The affected Australian communities were Katherine in Northern Territory, Oakey in Queensland and Williamtown in New South Wales. All residents identified in the Medicare Enrolment File (1983–2019)—a consumer directory for Australia’s universal healthcare—who ever lived in an exposure area (Katherine, Oakey and Williamtown), and a sample of those who ever lived in selected comparison areas, were linked to the Australian Cancer Database (1982–2017) and National Death Index (1980–2019). We estimated standardised incidence ratios (SIRs) for 23 cancer outcomes, four causes of death and three control outcomes, adjusting for sex, age and calendar time of diagnosis. We observed higher rates of prostate cancer (SIR=1·76, 95 % confidence interval (CI) 1·36–2·24) in Katherine; laryngeal cancer (SIR=2·71, 95 % CI 1·30–4·98), kidney cancer (SIR=1·82, 95 % CI 1·04–2·96) and coronary heart disease (CHD) mortality (SIR=1·81, 95 % CI 1·46–2·33) in Oakey; and lung cancer (SIR=1·83, 95 % CI 1·39–2·38) and CHD mortality (SIR=1·22, 95 % CI 1·01–1·47) in Williamtown. We also saw elevated SIRs for control outcomes. SIRs for all other outcomes and overall cancer were similar across exposure and comparison areas. There was limited evidence to support an association between living in a PFAS exposure area and risks of cancers or cause-specific deaths.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
凡人完成签到,获得积分20
1秒前
3秒前
凡人发布了新的文献求助10
3秒前
hzh发布了新的文献求助10
5秒前
5秒前
任老三完成签到,获得积分10
5秒前
5秒前
量子星尘发布了新的文献求助10
6秒前
HIT_C发布了新的文献求助10
6秒前
shaow完成签到,获得积分20
6秒前
7秒前
滑稽剑客发布了新的文献求助10
9秒前
kecheng应助sfsfes采纳,获得10
10秒前
GQL发布了新的文献求助10
11秒前
11秒前
荷包蛋完成签到,获得积分10
11秒前
huang1499发布了新的文献求助10
12秒前
最好发布了新的文献求助10
13秒前
13秒前
深情安青应助宿帅帅采纳,获得10
14秒前
EA7关注了科研通微信公众号
14秒前
14秒前
YamDaamCaa应助嘻嘻哈哈采纳,获得30
15秒前
桐桐应助清秀冰珍采纳,获得10
15秒前
积极晓绿发布了新的文献求助10
16秒前
16秒前
16秒前
酷波er应助滑稽剑客采纳,获得10
17秒前
17秒前
zhangsenbing发布了新的文献求助20
19秒前
giserhan发布了新的文献求助10
19秒前
20秒前
斯文败类应助森林采纳,获得10
20秒前
QQ关闭了QQ文献求助
23秒前
汉堡包应助友好的听寒采纳,获得10
23秒前
23秒前
23秒前
whatever应助XinG采纳,获得30
26秒前
宿帅帅发布了新的文献求助10
27秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Picture Books with Same-sex Parented Families: Unintentional Censorship 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
A Preliminary Study on Correlation Between Independent Components of Facial Thermal Images and Subjective Assessment of Chronic Stress 500
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3971541
求助须知:如何正确求助?哪些是违规求助? 3516239
关于积分的说明 11181643
捐赠科研通 3251428
什么是DOI,文献DOI怎么找? 1795874
邀请新用户注册赠送积分活动 876110
科研通“疑难数据库(出版商)”最低求助积分说明 805245