醌
生物放大
化学
环境化学
生物累积
蒽醌
有机化学
作者
Yi Li,Jingjing Zeng,Yongjin Liang,Yanlong Zhao,Shujun Zhang,Zhongyan Chen,Jiawen Zhang,Xiao‐Liang Shen,Jiabin Wang,Ying Zhang,Yuxin Sun
出处
期刊:Toxics
[MDPI AG]
日期:2024-05-28
卷期号:12 (6): 394-394
标识
DOI:10.3390/toxics12060394
摘要
As an antioxidant and antiozonant, N-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) is predominantly used in the rubber industry to prevent degradation. However, 6PPD can be ozonated to generate a highly toxic transformation product called N-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine quinone (6PPD-quinone), which is toxic to aquatic and terrestrial organisms. Thus, 6PPD and 6PPD-quinone, two emerging contaminants, have attracted extensive attention recently. This review discussed the levels and distribution of 6PPD and 6PPD-quinone in the environment and investigated their toxic effects on a series of organisms. 6PPD and 6PPD-quinone have been widely found in air, water, and dust, while data on soil, sediment, and biota are scarce. 6PPD-quinone can cause teratogenic, developmental, reproductive, neuronal, and genetic toxicity for organisms, at environmentally relevant concentrations. Future research should pay more attention to the bioaccumulation, biomagnification, transformation, and toxic mechanisms of 6PPD and 6PPD-quinone.
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