医学
抗体
融合蛋白
双特异性抗体
肿瘤科
融合
癌症研究
内科学
免疫学
单克隆抗体
基因
重组DNA
遗传学
语言学
哲学
生物
作者
Xiaohui Bai,Yihua Chen,Yihua Chen,Xiaoyun Liang,Hui Wang,Yuping Sun,Qian Chu,Yisheng Pan,Jingjing Cui,Jiancheng Fang,Wenbin Zhang,Qinghua Xu,Jun Zhang,X. Liu,Gang Dai,Lin Kang,Nailin Li,Min Fang,Hao Zhou,Liang Tang
标识
DOI:10.1016/j.annonc.2024.05.540
摘要
IBI363 has great potential to address unmet clinical need of immunotherapy (IO) resistant and cold tumors by blocking PD-1 checkpoint and cis-activating α-bias IL-2 to rejuvenate exhausted tumor-specific T cells.
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